The goal of this individual research project (CNRS, France) is to provide a methodology that allows building fluorinated azoles. In this context, we will focus on developing N-functionalization of commonly occurring N-heteroaryl in active pharmaceutical ingredients (APIs). Overall, we intend to enlarge the “magic methyl” story in drug discovery by another chapter.
In the second step (Sanofi, Germany), the synthetic methodologies studied by the DC will be applied through late-stage diversification of complex molecules and selected drug/candidates

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